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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AKAQNKPFYVV AESFKFVRLF PLNQQDVPDK FKYKADTLKV AQTGQDLKEE HPWVDYTAPS LITLLFTDLG VLTPSAVSDE LIKLYL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-2B; eIF-2B GDP-GTP exchange factor subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha; EIF2B1; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; unnamed protein product
Gene Aliases: EIF2B; EIF2BA; EIF2Balpha; VWM1
UniProt ID: (Human) Q14232
Entrez Gene ID: (Human) 1967
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