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Invitrogen
NPNT Polyclonal Antibody
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Product Details
PA5-65600
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NPNT. Recombinant protein control fragment (Product #RP-104893).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TVDNRVQTDPQ KPRGDVFIPR QPSNDLFEIF EIERGVSADD EAKDDPGVLV HSCNFDHGLC GWIREKDNDL HWEPIRDPAG GQYLTVSAAK APGGKAARLV LPLGRLMHSG DLCLSFRHKV TGLHSGTLQV FVRKHGAHGA ALWGRNGGHG WRQTQITL
Highest antigen sequence identity to the following orthologs - mouse 92%, rat 94%.
Target Information
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Nephronectin; Preosteoblast EGF-like repeat protein with MAM domain; Protein EGFL6-like; unnamed protein product
Gene Aliases: EGFL6L; NPNT; POEM; UNQ295/PRO334
UniProt ID: (Human) Q6UXI9
Entrez Gene ID: (Human) 255743
ureteric bud development
branching involved in ureteric bud morphogenesis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
positive regulation of cell-substrate adhesion
cell differentiation
extracellular matrix organization
positive regulation of transforming growth factor beta receptor signaling pathway
cell-cell adhesion mediated by integrin
establishment of protein localization
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
smooth muscle cell differentiation
positive regulation of ERK1 and ERK2 cascade
cellular response to tumor necrosis factor
pilomotor reflex
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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