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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ASC1 Antibodies

          Invitrogen

          ASC1 Polyclonal Antibody

          View all (9) ASC1 antibodies

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          Cite ASC1 Polyclonal Antibody

          • Antibody Testing Data (1)
          ASC1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ASC1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          ASC1 Antibody (PA5-65633) in ICC/IF

          Immunofluorescent staining of ASC1 in human cell line U-2 OS shows localization to nucleoplasm and nuclear bodies. Samples were probed using an ASC1 Polyclonal Antibody (Product # PA5-65633). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ASC1 Antibody in Immunocytochemistry (ICC/IF)
          ASC1 Polyclonal Antibody

          Product Details

          PA5-65633

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human ASC1. Recombinant protein control fragment (Product #RP-106304).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2663365

          Product Specific Information

          Immunogen sequence: KAFRSSGFGLE FNSFQHQLRI QDQEFQEGFD GGWCLSVHQP WASLLVRGIK RVEGRSWYTP HRGRLWIAAT AKKPSPQEVS ELQATYRLLR GKDVEFPNDY PSGCLLGCVD LIDCLSQKQF KEQFPDISQE SDSPFVF

          Highest antigen sequence identity to the following orthologs - mouse 89%, rat 88%.

          Target Information

          Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Activating signal cointegrator 1; ASC-1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; zinc finger, C2HC5-type

          View more View less

          Gene Aliases: ASC-1; ASC1; HsT17391; RQT4; SMABF1; TRIP4; ZC2HC5

          View more View less

          UniProt ID: (Human) Q15650

          View more View less

          Entrez Gene ID: (Human) 9325

          View more View less

          Function(s)
          protease binding transcription coactivator activity protein binding zinc ion binding ligand-dependent nuclear receptor binding estrogen receptor binding histone acetyltransferase binding ubiquitin-like protein ligase binding transcription cofactor gene-specific transcriptional regulator
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated intracellular estrogen receptor signaling pathway positive regulation of transcription, DNA-templated toxin transport
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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