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Invitrogen
CD179b Polyclonal Antibody
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Product Details
PA5-65649
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CD179b. Recombinant protein control fragment (Product #RP-106324).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GFQSKHNSVTH VFGSGTQLTV LSQPK
Highest antigen sequence identity to the following orthologs - mouse 46%, rat 50%.
Target Information
The preB cell receptor, CD179b, is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation and differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda-5; IGLJ IGLL; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; Immunoglobulin-related protein 14.1; lambda5; Pre-B lymphocyte-specific protein-2
Gene Aliases: 14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGLL1; IGO; IGVPB; VPREB2
UniProt ID: (Human) P15814
Entrez Gene ID: (Human) 3543
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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