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Invitrogen
USP36 Polyclonal Antibody
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Product Details
PA5-65745
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human USP36. Recombinant protein control fragment (Product #RP-106421).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EDGHLKCPRSA KPQDAVVPES SSCAPSANGW CPGDRMGLSQ APPVSWNGER ESDVVQELLK YSSDKAYGRK VLTWDGKMSA VSQDAIEDSR QARTETVVDD WDEEFDRGKE KKIKKFKREK RRNFNAFQKL QTRRNFWSVT HPAK
Highest antigen sequence identity to the following orthologs - mouse 70%, rat 68%.
Target Information
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36; unnamed protein product
Gene Aliases: DUB1; KIAA1453; USP36
UniProt ID: (Human) Q9P275
Entrez Gene ID: (Human) 57602
chromatin organization
chromatin remodeling
proteolysis
nucleolus organization
negative regulation of macroautophagy
protein deubiquitination
regulation of protein stability
regulation of apoptotic process
protein stabilization
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of rRNA processing
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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