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          • Primary Antibodies ›
          • INTS1 Antibodies

          Invitrogen

          INTS1 Polyclonal Antibody

          View all (5) INTS1 antibodies

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          Cite INTS1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          INTS1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          INTS1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          INTS1 Antibody (PA5-65756) in ICC/IF

          Immunofluorescent staining of INTS1 in human cell line MCF7 shows localization to nucleoplasm. Samples were probed using an INTS1 Polyclonal Antibody (Product # PA5-65756). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          INTS1 Antibody in Immunocytochemistry (ICC/IF)
          INTS1 Polyclonal Antibody

          Product Details

          PA5-65756

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human INTS1. Recombinant protein control fragment (Product #RP-106434).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Amount

          5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2664028

          Product Specific Information

          Immunogen sequence: KLDGLIHRFIT LLADTSDSRA LENRGADASM ACRKLAVAHP LLLLRHLPMI AALLHGRTHL NFQEFRQQNH LSCF

          Highest antigen sequence identity to the following orthologs - mouse 88%, rat 25%.

          Target Information

          INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Int1; Integrator complex subunit 1

          View more View less

          Gene Aliases: INT1; INTS1; KIAA1440; NDCAGF; NET28; UNQ1821/PRO3434

          View more View less

          UniProt ID: (Human) Q8N201

          View more View less

          Entrez Gene ID: (Human) 26173

          View more View less

          Function(s)
          protein binding
          Process(es)
          blastocyst growth inner cell mass cell proliferation embryo implantation snRNA processing regulation of transcription elongation from RNA polymerase II promoter U2 snRNA 3'-end processing negative regulation of apoptotic process RNA polymerase II transcription initiation surveillance
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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