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Invitrogen
VPS54 Polyclonal Antibody
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Product Details
PA5-65985
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human VPS54. Recombinant protein control fragment (Product #RP-105029).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VDIMVSEDMKL TDSELGKLAN NIQELLYSAS DICHDRAVKF LMSRAKDGFL EKLNSMEFIT LSRLMETFIL DTEQICGRKS TSLLGAL
Highest antigen sequence identity to the following orthologs - mouse 86%, rat 89%.
Target Information
This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hepatocellular carcinoma protein 8; hVps54L; protein phosphatase 1, regulatory subunit 164; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p; unnamed protein product; vacuolar protein sorting 54 homolog; Vacuolar protein sorting-associated protein 54; VPS54, GARP complex subunit
Gene Aliases: HCC8; hVps54L; PPP1R164; SLP-8p; VPS54; VPS54L; WR
UniProt ID: (Human) Q9P1Q0
Entrez Gene ID: (Human) 51542
in utero embryonic development
apoptotic DNA fragmentation
protein targeting to lysosome
protein targeting to vacuole
cellular calcium ion homeostasis
Golgi to vacuole transport
striated muscle contraction
mitochondrion organization
vacuole organization
lysosomal transport
neuromuscular synaptic transmission
skeletal muscle tissue development
protein localization
gene expression
ubiquitin homeostasis
microglia differentiation
protein transport
respiratory electron transport chain
sphingolipid catabolic process
protein localization to cell surface
limb morphogenesis
post-embryonic forelimb morphogenesis
synaptic transmission, glutamatergic
regulation of growth
retrograde transport, endosome to Golgi
protein targeting to ER
response to antibiotic
spermatid differentiation
skeletal muscle tissue growth
astrocyte differentiation
neuron projection morphogenesis
homeostasis of number of cells
homeostasis of number of cells within a tissue
musculoskeletal movement
neuron apoptotic process
response to calcium ion
synaptic transmission, GABAergic
L-glutamate import
neurofilament cytoskeleton organization
limb development
motor behavior
thrombin receptor signaling pathway
cellular response to progesterone stimulus
vesicle-mediated cholesterol transport
motor neuron apoptotic process
neural tissue regeneration
neuroinflammatory response
negative regulation of motor neuron apoptotic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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