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Invitrogen
TMEM135 Polyclonal Antibody
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Product Details
PA5-66032
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human TMEM135. Recombinant protein control fragment (Product #RP-103913).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SALRFIVGKEE IPTHSFSPEA AYAKVEQKRE QHEEKPRRMN MIGLVRKFVD SICKHGPRHR CCKHYEDNC
Highest antigen sequence identity to the following orthologs - mouse 81%, rat 81%.
Target Information
The transmembrane protein 135 (TMEM135), also known as peroxisomal membrane protein 52 (PMP52), was initially identified as a protein that might be critical for adipogenesis and osteoblastogenesis. Further studies have indicated that TMEM135 may be part of a regulatory circuit that plays an important role in fat metabolism and energy expenditure in both C. elegans as well as mammalian organisms. Finally, recent experiments has suggested that TMEM135 may be an additional driver of breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Peroxisomal membrane protein 52; peroxisomal protein 52; PMP52; Transmembrane protein 135; unnamed protein product
Gene Aliases: PMP52; TMEM135
UniProt ID: (Human) Q86UB9
Entrez Gene ID: (Human) 65084
regulation of oxidative phosphorylation
retinal pigment epithelium development
unsaturated fatty acid biosynthetic process
mitochondrion organization
peroxisome organization
response to cold
long-chain fatty acid transport
response to food
alpha-linolenic acid metabolic process
long-chain fatty acid biosynthetic process
regulation of mitochondrial fission
fatty acid derivative biosynthetic process
fatty acid derivative transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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