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Invitrogen
DCLRE1B Polyclonal Antibody
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Product Details
PA5-66733
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human DCLRE1B. Recombinant protein control fragment (Product #RP-107387).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VVPIVSRRPCG GFQDSLSPRI SVPLIPDSVQ QYMSSSSRKP SLLWLLERRL KRPRTQGVVF ESPEESADQS QADRDSKKAK KEKLSPWPAD LEKQPSHHPL RIKKQ
Highest antigen sequence identity to the following orthologs - mouse 71%, rat 71%.
Target Information
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5' exonuclease Apollo; Beta-lactamase DCLRE1B; DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1B protein; PSO2 homolog; SNM1 homolog B; SNMIB; unnamed protein product
Gene Aliases: APOLLO; DCLRE1B; DKCB8; SNM1B; SNMIB
UniProt ID: (Human) Q9H816
Entrez Gene ID: (Human) 64858
telomere maintenance
DNA repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
telomere maintenance via telomere lengthening
telomere capping
telomeric loop formation
protection from non-homologous end joining at telomere
telomeric 3' overhang formation
interstrand cross-link repair
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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