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          • Primary Antibodies ›
          • DOC2A Antibodies

          Invitrogen

          DOC2A Polyclonal Antibody

          View all (7) DOC2A antibodies

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          Cite DOC2A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          DOC2A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          DOC2A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          DOC2A Antibody (PA5-66787) in ICC/IF

          Immunofluorescent staining of DOC2A in human cell line U-2 OS shows localization to nucleus and cell junctions. Samples were probed using a DOC2A Polyclonal Antibody (Product # PA5-66787). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DOC2A Antibody in Immunocytochemistry (ICC/IF)
          DOC2A Polyclonal Antibody

          Product Details

          PA5-66787

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human DOC2A. Recombinant protein control fragment (Product #RP-107445).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2663283

          Product Specific Information

          Immunogen sequence: PAALLGATTPE DGAEVDSYDS DDATALG

          Highest antigen sequence identity to the following orthologs - mouse 93%, rat 93%.

          Target Information

          There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Doc2; doc2-alpha; Double C2-like domain-containing protein alpha; double C2-like domains, alpha; unnamed protein product

          View more View less

          Gene Aliases: Doc2; DOC2A

          View more View less

          UniProt ID: (Human) Q14183

          View more View less

          Entrez Gene ID: (Human) 8448

          View more View less

          Function(s)
          protein binding calcium-dependent phospholipid binding metal ion binding
          Process(es)
          exocytosis chemical synaptic transmission nervous system development synaptic vesicle exocytosis regulation of calcium ion-dependent exocytosis positive regulation of calcium ion-dependent exocytosis spontaneous neurotransmitter secretion calcium-dependent activation of synaptic vesicle fusion
          It has to be done as per old AB suggested Products section.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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