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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PCPTP1 Antibodies

          Invitrogen

          PCPTP1 Polyclonal Antibody

          View all (12) PCPTP1 antibodies

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          Cite PCPTP1 Polyclonal Antibody

          • Antibody Testing Data (1)
          PCPTP1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PCPTP1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PCPTP1 Antibody (PA5-67143) in ICC/IF

          Immunofluorescent staining of PCPTP1 in human cell line U-2 OS shows localization to plasma membrane. Samples were probed using a PCPTP1 Polyclonal Antibody (Product # PA5-67143). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PCPTP1 Antibody in Immunocytochemistry (ICC/IF)
          PCPTP1 Polyclonal Antibody

          Product Details

          PA5-67143

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human PCPTP1. Recombinant protein control fragment (Product #RP-105518).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2663333

          Product Specific Information

          Immunogen sequence: ERFQLSLRQDK EKNQEIHLSP ITLQPALSEA KTVHSMVQPE QAPKVLNVVV DPQGRGAPEI KATTATSVCP SPFK

          Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.

          Target Information

          The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Ch-1 PTPase; Ch-1PTPase; ECPPT; NC-PTPCOM1; protein tyrosine phosphatase Cr1PTPase; protein tyrosine phosphatase, receptor type, R; protein-tyrosine phosphatase NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; R-PTP-R; Receptor-type tyrosine-protein phosphatase R

          View more View less

          Gene Aliases: EC-PTP; ECPTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ; PTPRR

          View more View less

          UniProt ID: (Human) Q15256

          View more View less

          Entrez Gene ID: (Human) 5801

          View more View less

          Function(s)
          protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity protein binding protein kinase binding
          Process(es)
          in utero embryonic development protein dephosphorylation negative regulation of epithelial cell migration neuron differentiation peptidyl-tyrosine dephosphorylation ERBB2 signaling pathway negative regulation of ERK1 and ERK2 cascade regulation of homophilic cell adhesion
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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