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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: REGHCYKLVSI ISKTVVLGLA LRREGPAPLH FLLLTDTPRF ALPQGLLAGD PRVERLVRDS ASYCRERFDP DEY
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GRB2-associated and regulator of MAPK protein 2; GRB2-associated and regulator of MAPK1-like
Gene Aliases: FAM59B; GAREM2; GAREML; HRIHFB2063; KIAA2038
Entrez Gene ID: (Human) 150946
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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