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Invitrogen
FAPP2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-67238
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human FAPP2. Recombinant protein control fragment (Product #RP-107874).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TSELLYRTPPG SPQLAMLKSS KMKHPIIPIH NSLERQMELS TCENGSLNME INGEEEILMK NKNSLYLKSA EIDCSISSEE NTDDNITVQG EIMK
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 78%.
Target Information
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FAPP2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol 4-phosphate adaptor protein-2; phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; serologically defined breast cancer antigen NY-BR-86; unnamed protein product
Gene Aliases: FAPP2
UniProt ID: (Human) Q96JA3
Entrez Gene ID: (Human) 84725
protein binding
glycolipid transporter activity
small GTPase binding
glycosphingolipid binding
glycolipid binding
phosphatidylinositol-4-phosphate binding
ceramide binding
intermembrane lipid transfer activity
sphingolipid transfer activity
molecular carrier activity
cerebroside transfer activity
ceramide 1-phosphate binding
ceramide 1-phosphate transporter activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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