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Invitrogen
GTF2H4 Polyclonal Antibody
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Product Details
PA5-67338
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human GTF2H4. Recombinant protein control fragment (Product #RP-107987).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EFSKAQEESTG LLSGLRIWHT QLLPGGLQGL ILNPIFRQNL RIALLGGGKA WSDDTSQLGP DKHARDVPSL DKYAEERWEV VL
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
Target Information
GTF2H4 belongs to the TFB2 family. It is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; General transcription factor IIH subunit 4; general transcription factor IIH, polypeptide 4, 52kDa; TFIIH basal transcription factor complex p52 subunit
Gene Aliases: GTF2H4; P52; TFB2; TFIIH
UniProt ID: (Human) Q92759
Entrez Gene ID: (Human) 2968
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
ATP-dependent DNA helicase activity
protein kinase activity
protein binding
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
nucleotide-excision repair, DNA duplex unwinding
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
nucleotide-excision repair, DNA incision
phosphorylation of RNA polymerase II C-terminal domain
global genome nucleotide-excision repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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