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Invitrogen
Necdin Polyclonal Antibody
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Product Details
PA5-67347
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Necdin. Recombinant protein control fragment (Product #RP-107999).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AQLVQKAHELM WYVLVKDQKK MIIWFPDMVK DVIGSYKKWC RSILRRTSLI
Highest antigen sequence identity to the following orthologs - mouse 88%, rat 88%.
Target Information
This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: melanoma antigen family member protein; MAGE protein; Necdin; necdin homolog; necdin homolog (mouse) isoform NDN_1; necdin homolog (mouse) isoform NDN_2; necdin homolog (mouse) isoform NDN_3; necdin homolog (mouse) isoform NDN_4; necdin homolog (mouse) isoform NDN_5; necdin, melanoma antigen (MAGE) family member; necdin-like protein; Prader-Willi syndrome chromosome region; unnamed protein product
Gene Aliases: HsT16328; NDN; PWCR
UniProt ID: (Human) B2R6Z5
Entrez Gene ID: (Human) 4692
negative regulation of transcription from RNA polymerase II promoter
neuron migration
respiratory system process
regulation of transcription, DNA-templated
axonogenesis
axonal fasciculation
central nervous system development
respiratory gaseous exchange
glial cell migration
post-embryonic development
sensory perception of pain
neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
neurotrophin TRK receptor signaling pathway
neuron development
axon extension
multicellular organismal homeostasis
genetic imprinting
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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