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Invitrogen
ETK Polyclonal Antibody
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Product Details
PA5-81915
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human BMX. Recombinant protein control fragment (Product #RP-91993).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KFLCCQQSCK AAPGCTLWEA YANLHTAVNE EKHRVPTFPD RVLKIPRAVP VLKMDAPSSS TTLAQYDNES KKNYGSQPPS SSTSLAQYDS NSKKIYGSQP NFNMQYIPRE DFPDWWQVR
Highest antigen sequence indentity to the following orthologs: Mouse - 64%, Rat - 54%.
Target Information
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bone marrow tyrosine kinase gene in chromosome X protein; BTK-like on X chromosome; Cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase
Gene Aliases: BMX; ETK; PSCTK2; PSCTK3
UniProt ID: (Human) A6NIH9
Entrez Gene ID: (Human) 660
NK T cell differentiation
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
mesoderm development
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
protein autophosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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