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Invitrogen
MYO5A Polyclonal Antibody
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Product Details
PA5-81932
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYO5A. Recombinant protein control fragment (Product #RP-95381).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QNLQLPPEAR IEASLQHEIT RLTNENLDLM EQLEKQDKTV RKLKKQLKVF AKKIGELEVG QMENISPGQI IDEPIRPVNI PRKEKDFQGM LEYKKEDEQK LVKNLILELK PRGVAVNLIP G
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 99%.
Target Information
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-associated molecular motor; alternatively spliced; molecular motor; Dilute myosin heavy chain, non-muscle; motor protein; Myosin heavy chain 12; myosin V; myosin VA (heavy chain 12, myoxin); myosin, heavy polypeptide kinase; Myosin-12; myosin-Va; Myoxin; OTTMUSP00000017756; OTTMUSP00000019176; OTTMUSP00000046608; Unconventional myosin-Va; unnamed protein product
Gene Aliases: GS1; MYH12; MYO5; MYO5A; MYR12
UniProt ID: (Human) Q9Y4I1
Entrez Gene ID: (Human) 4644
post-Golgi vesicle-mediated transport
endocytosis
actin filament organization
protein transport
vesicle-mediated transport
actin filament-based movement
vesicle transport along actin filament
melanosome transport
cellular response to insulin stimulus
protein localization to plasma membrane
regulation of Golgi organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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