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Invitrogen
hnRNP A2B1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-81963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HNRNPA2B1. Recombinant protein control fragment (Product #RP-94771).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VMRDPASKRS RGFGFVTFSS MAEVDAAMAA RPHSIDGRVV EPKRAVAREE SGKPGAHVTV KKLFVGGIKE DTEEHHLRDY FEEYGKIDTI EIITDRQSGK KRGFGFVTFD DHDPVDKIVL QKYHTINGHN AEVRKAL
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp779B0244; epididymis secretory sperm binding protein; FLJ22720; heterogeneous nuclear ribonucleoprotein A2; heterogeneous nuclear ribonucleoprotein B0a; heterogeneous nuclear ribonucleoprotein B0b; heterogeneous nuclear ribonucleoprotein B1; heterogenous nuclear ribonucleoprotein A2/B1; hnRNP; hnRNP A2 / hnRNP B1; hnRNP A2 protein; hnRNP A2/B1; hnRNP B1 protein; HNRNPA2B1/MYC fusion; nuclear ribonucleoprotein particle A2 protein; OTTHUMP00000202465; OTTHUMP00000202466; unnamed protein product
Gene Aliases: 9130414A06Rik; hnRNP; hnrnp-A; HNRNPA2; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; IBMPFD2; OPDM2; OPMD2; RNPA2; SNRPB1
UniProt ID: (Human) P22626, (Mouse) O88569, (Rat) A7VJC2
Entrez Gene ID: (Human) 3181, (Mouse) 53379, (Rat) 362361
nucleic acid binding
RNA binding
mRNA 3'-UTR binding
protein binding
miRNA binding
identical protein binding
single-stranded telomeric DNA binding
DNA polymerase binding
pre-mRNA intronic binding
G-rich strand telomeric DNA binding
molecular condensate scaffold activity
N6-methyladenosine-containing RNA binding
regulatory region RNA binding
mRNA CDS binding
mRNA splicing, via spliceosome
mRNA processing
mRNA export from nucleus
primary miRNA processing
DNA geometric change
RNA transport
mRNA transport
positive regulation of telomere maintenance via telomere lengthening
miRNA transport
negative regulation of transcription from RNA polymerase II promoter
telomere capping
negative regulation of mRNA splicing, via spliceosome
negative regulation of mRNA metabolic process
male gonad development
lung development
oligodendrocyte differentiation
response to mineralocorticoid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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