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Invitrogen
MYO1C Polyclonal Antibody
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Product Details
PA5-81969
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYO1C. Recombinant protein control fragment (Product #RP-100988).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GEEETLRRLG LERNPQSYLY LVKGQCAKVS SINDKSDWKV VRKALTVIDF TEDEVEDLLS IVASVLHLGN IHFAANEESN AQVTTENQLK YLTRLLSVEG STLREALTHR KIIAKGEELL SPLNLEQAAY ARDALAKAVY SRTFTWLV
Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 96%.
Target Information
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23903; MMI-beta; Myosin I beta; myosin-I beta; myosin-Ic; nuclear myosin I; Unconventional myosin-Ic; unnamed protein product
Gene Aliases: MMI-beta; MMIb; MYO1C; MyoIC; myr2; NMI
UniProt ID: (Human) O00159
Entrez Gene ID: (Human) 4641
chromatin remodeling
protein targeting to membrane
endocytosis
actin filament organization
actin filament-based movement
vesicle transport along actin filament
positive regulation of cell migration
vascular endothelial growth factor signaling pathway
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
cellular response to interferon-gamma
positive regulation of protein targeting to membrane
positive regulation of cellular response to insulin stimulus
regulation of bicellular tight junction assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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