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Invitrogen
C1QA Polyclonal Antibody
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Product Details
PA5-82013
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C1QA. Recombinant protein control fragment (Product #RP-95413).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GSPGNIKDQP RPAFSAIRRN PPMGGNVVIF DTVITNQEEP YQNHSGRFVC TVPGYYYFTF QVLSQWEICL SIVSSSRGQV RRSLGFCDTT NKGLFQVVSG GMVLQLQQGD QVWVEKDPKK GHIYQGSEAD SVFS
Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 72%.
Target Information
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: complement C1q chain A; Complement C1q subcomponent subunit A; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain; unnamed protein product
Gene Aliases: C1QA; C1QD1
UniProt ID: (Human) P02745
Entrez Gene ID: (Human) 712
microglial cell activation
immune system process
complement activation
complement activation, classical pathway
cell-cell signaling
neuron remodeling
innate immune response
astrocyte activation
synapse organization
synapse pruning
complement-mediated synapse pruning
vertebrate eye-specific patterning
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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