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Invitrogen
USP11 Polyclonal Antibody
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Product Details
PA5-82061
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human USP11. Recombinant protein control fragment (Product #RP-92187).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ESGRERPLRA GESWFLVEKH WYKQWEAYVQ GGDQDSSTFP GCINNATLFQ DEINWRLKEG LVEGEDYVLL PAAAWHYLVS WYGLEHGQPP IERKVIELPN IQKVEVYPVE LLLVRHNDLG KSHTVQFS
Highest antigen sequence indentity to the following orthologs: Mouse - 77%, Rat - 77%.
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deubiquitinating enzyme 11; RP4-659F15.2; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11
Gene Aliases: UHX1
Entrez Gene ID: (Human) 8237
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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