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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LLYTAKEAGG NPKQAAHTQE ALEEAVQMMT EAVEDLTTTL NEAASAAGVV GGMVDSITQA INQLDEGPMG EPEGSFVDYQ TTMVRTAKAI AVTVQEMVTK SNTSP
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 99%.
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cytoskeletal protein
Gene Aliases: ILWEQ; talin-1; TLN
UniProt ID: (Human) Q9Y490
Entrez Gene ID: (Human) 7094
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