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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HP1 gamma Antibodies

          Invitrogen

          HP1 gamma Polyclonal Antibody

          Advanced Verification
          View all (28) HP1 gamma antibodies

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          Cite HP1 gamma Polyclonal Antibody

          • Antibody Testing Data (5)
          • Advanced Verification (1)
          HP1 gamma Antibody in Immunocytochemistry (ICC/IF)
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          HP1 gamma Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          HP1 gamma Antibody (PA5-82181) in ICC/IF

          Immunofluorecent analysis of HP1 gamma in human cell line U-251 MG using HP1 gamma Polyclonal Antibody (Product # PA5-82181). Staining shows localization to nucleoplasm and nuclear bodies. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          HP1 gamma Antibody in Immunocytochemistry (ICC/IF)
          HP1 gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HP1 gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HP1 gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HP1 gamma Antibody in Western Blot (WB)
          HP1 gamma Antibody
          HP1 gamma Polyclonal Antibody

          Product Details

          PA5-82181

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human CBX3. Recombinant protein control fragment (Product #RP-102507).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2789342

          Product Specific Information

          Immunogen sequence: RVVNGKVEYF LKWKGFTDAD NTWEPEENLD CPELIEAFLN SQKAGKEKDG TKRKSLSDSE SDDSKSKKKR DAADKPRGFA RGLDPERIIG ATDSSGELMF LMKWKDSDEA

          Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

          Target Information

          At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; Modifier 2 protein; OTTHUMP00000202463

          View more View less

          Gene Aliases: CBX3; HECH; HP1-GAMMA; HP1Hs-gamma

          View more View less

          UniProt ID: (Human) Q13185

          View more View less

          Entrez Gene ID: (Human) 11335

          View more View less

          Function(s)
          protein binding enzyme binding protein domain specific binding identical protein binding histone methyltransferase binding
          Process(es)
          chromatin remodeling transcription, DNA-templated covalent chromatin modification negative regulation of transcription, DNA-templated rhythmic process cellular response to dexamethasone stimulus
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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