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Invitrogen
hnRNP D Polyclonal Antibody
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Product Details
PA5-82182
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HNRNPD. Recombinant protein control fragment (Product #RP-102523).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RGFCFITFKE EEPVKKIMEK KYHNVGLSKC EIKVAMSKEQ YQQQQQWGSR GGFAGRARGR GGDQQSGYGK VS
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARE-binding protein AUFI, type A; AU-rich element RNA binding protein 1, 37kDa; AU-rich element RNA-binding protein 1; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0
Gene Aliases: AUF1; AUF1A; HNRNPD; hnRNPD0; HNRPD; P37
UniProt ID: (Human) Q14103
Entrez Gene ID: (Human) 3184
mRNA splicing, via spliceosome
liver development
transcription, DNA-templated
regulation of transcription, DNA-templated
RNA processing
RNA catabolic process
gene expression
response to fluoxetine
cerebellum development
regulation of circadian rhythm
regulation of mRNA stability
positive regulation of translation
positive regulation of transcription, DNA-templated
mRNA stabilization
response to calcium ion
response to electrical stimulus
3'-UTR-mediated mRNA destabilization
cellular response to amino acid stimulus
cellular response to estradiol stimulus
cellular response to nitric oxide
circadian regulation of translation
response to rapamycin
response to sodium phosphate
cellular response to putrescine
hepatocyte dedifferentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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