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Invitrogen
CK2 beta Polyclonal Antibody
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Product Details
PA5-82226
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CSNK2B. Recombinant protein control fragment (Product #RP-101869).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PHYRQALDMI LDLEPDEELE DNPNQSDLIE QAAEMLYGLI HARYILTNRG IAQMLEKYQQ GDFGYCPRVY CENQPMLPIG LSDIPGEAMV KLYCPKCMDV YTPKSSRHHH TDGAYFGTGF PHMLFMVHPE YRPKRPANQF VPRLY
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Target Information
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; Casein kinase II beta subunit; Casein kinase II subunit beta; CK II beta; CSNK2B; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; DADB-127H9.2; MGC138222; MGC138224; Phosvitin; Protein G5a; protein kinase; unnamed protein product
Gene Aliases: CK2B; CK2N; Ckb1; Ckb2; CSK2B; CSNK2B; G5A; POBINDS
UniProt ID: (Human) P67870
Entrez Gene ID: (Human) 1460
chromatin binding
protein serine/threonine kinase activity
receptor binding
protein binding
protein kinase regulator activity
protein domain specific binding
protein binding, bridging
identical protein binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
signal transduction
negative regulation of cell proliferation
Wnt signaling pathway
peptidyl-threonine phosphorylation
release from viral latency
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of activin receptor signaling pathway
adiponectin-activated signaling pathway
negative regulation of blood vessel endothelial cell migration
positive regulation of SMAD protein import into nucleus
endothelial tube morphogenesis
protein-containing complex assembly
symbiont-mediated disruption of host cell PML body
negative regulation of viral life cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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