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Invitrogen
HK1 Polyclonal Antibody
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Product Details
PA5-82279
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HK1. Recombinant protein control fragment (Product #RP-89763).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LPTFVRSIPD GSEKGDFIAL DLGGSSFRIL RVQVNHEKNQ NVHMESEVYD TPENIVHGSG SQLFDHVAEC LGDFMEKRKI KDKKLPVGFT FSFPCQQSKI DEAILITWTK RFKASGVEGA DVVKLLN
Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 97%.
Target Information
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain form hexokinase; glycolytic enzyme; hexokinase IR; Hexokinase type I; Hexokinase-1; Hexokinase-A; HK I; HK1-td; Neuropathy, hereditary motor and sensory, Russe type; unnamed protein product
Gene Aliases: CNSHA5; hexokinase; HK; HK1; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; NEDVIBA; NMSR; RP79
UniProt ID: (Human) P19367
Entrez Gene ID: (Human) 3098
nucleotide binding
catalytic activity
glucokinase activity
hexokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
mannokinase activity
peptidoglycan binding
glucosamine kinase activity
cellular glucose homeostasis
immune system process
positive regulation of cytokine production involved in immune response
carbohydrate metabolic process
fructose 6-phosphate metabolic process
glucose metabolic process
mannose metabolic process
glycolytic process
inflammatory response
GDP-mannose biosynthetic process
hexose metabolic process
organophosphate metabolic process
positive regulation of interleukin-1 beta production
innate immune response
carbohydrate phosphorylation
glucose 6-phosphate metabolic process
canonical glycolysis
GDP-mannose biosynthetic process from mannose
establishment of protein localization to mitochondrion
maintenance of protein location in mitochondrion
carbohydrate derivative metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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