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Invitrogen
Annexin A4 Polyclonal Antibody
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Product Details
PA5-82296
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ANXA4. Recombinant protein control fragment (Product #RP-88718).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KGGTVKAASG FNAMEDAQTL RKAMKGLGTD EDAIISVLAY RNTAQRQEIR TAYKSTIGRD LIDDLKSELS GNFEQVIVGM MTPTVLYDVQ ELRRAMKGAG TDEGCLIEIL ASRTPEEIRR ISQTYQQQ
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 93%.
Target Information
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 35-beta calcimedin; 36 kDa zymogen granule membrane-associated protein; Annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); Annexin-4; ANXA 4; ANXA4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; epididymis secretory protein Li 274; Lipocortin IV; P32.5; PAP-II; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; unnamed protein product; ZAP 36/annexin IV; ZAP36
Gene Aliases: AI265406; AIV; ANX4; ANXA4; AW106930; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; Xanx-4; ZAP36
UniProt ID: (Human) P09525, (Mouse) P97429
Entrez Gene ID: (Human) 307, (Rat) 79124, (Mouse) 11746
negative regulation of transcription from RNA polymerase II promoter
signal transduction
Notch signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
epithelial cell differentiation
negative regulation of interleukin-8 production
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of transcription from RNA polymerase II promoter
exocytosis
negative regulation of NF-kappaB transcription factor activity
negative regulation of interleukin-8 secretion
kidney development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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