Search
Invitrogen
ACADL Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-82450
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ACADL. Recombinant protein control fragment (Product #RP-88960).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GEERLETPSA KKLTDIGIRR IFSPEHDIFR KSVRKFFQEE VIPHHSEWEK AGEVSREVWE KAGKQGLLGV NIAEHLGGIG GDLYSAAIVW EEQAYSNCSG PGFSIHSGIV MSYITNHGSE EQIKHFIPQM T
Highest antigen sequence indentity to the following orthologs: Mouse - 83%, Rat - 82%.
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD; LCAD long chain acyl-CoA dehydrogenase; long-chain acyl-CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial; Medium-chain acyl-CoA dehydrogenase, mitochondrial; unnamed protein product
Gene Aliases: AA960361; ACAD4; ACADL; ACOADA; AU018452; C79855; LCAD
UniProt ID: (Human) P28330, (Mouse) P51174, (Rat) P15650
Entrez Gene ID: (Human) 33, (Mouse) 11363, (Rat) 25287
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
protein homodimerization activity
flavin adenine dinucleotide binding
fatty-acyl-CoA binding
palmitoyl-CoA oxidase activity
dehydrogenase
temperature homeostasis
lipid metabolic process
fatty acid metabolic process
lipid catabolic process
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
regulation of cholesterol metabolic process
positive regulation of cold-induced thermogenesis
metabolic process
cellular lipid catabolic process
protein homotetramerization
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support