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Invitrogen
SERPINB6 Polyclonal Antibody
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Product Details
PA5-82469
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SERPINB6. Recombinant protein control fragment (Product #RP-89219).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LVLVNAVYFR GNWDEQFDKE NTEERLFKVS KNEEKPVQMM FKQSTFKKTY IGEIFTQILV LPYVGKELNM IIMLPDETTD LRTVEKELTY EKFVEWTRLD MMDEEEVEVS LPRFKLEESY DMESVLRNLG MTD
Highest antigen sequence indentity to the following orthologs: Rat - 79%, Mouse - 77%.
Target Information
The protein encoded by this gene is a member of the serpin superfamily, and ovalbumin-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAP; Cytoplasmic antiproteinase; DKFZp686I04222; MGC111370; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); RP1-90J20.6; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; Serpin B6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; unnamed protein product
Gene Aliases: CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SERPINB6; SPI3
UniProt ID: (Human) P35237
Entrez Gene ID: (Human) 5269
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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