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Invitrogen
PTPRE Polyclonal Antibody
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Product Details
PA5-82543
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTPRE. Recombinant protein control fragment (Product #RP-90955).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NGILEEQEQQ RVMLLSRSPS GPKKYFPIPV EHLEEEIRIR SADDCKQFRE EFNSLPSGHI QGTFELANKE ENREKNRYPN ILPNDHSRVI LSQLDGIPCS DYINASYIDG YKEKNKFIAA QGPKQE
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 98%.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTP epsilon; PTPvarepsilon; Receptor-type tyrosine-protein phosphatase epsilon
Gene Aliases: HPTPE; PTPE; PTPRE; R-PTP-EPSILON
UniProt ID: (Human) P23469
Entrez Gene ID: (Human) 5791
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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