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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: RVLVHTSVSP SPDNLRRFAL EHEASDLVEI YLWKLVKGIF HLTQIKKVRK QDFQKEAQHF RLLAGPHEGH WNVFLAQTLE LKVTASPDKV TKT
Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 77%.
CHRDL2 encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: breast tumor novel factor 1; CHL2; chordin-related protein 2; FKSG37; unnamed protein product
Gene Aliases: BNF1; CHL2
UniProt ID: (Human) Q6WN34
Entrez Gene ID: (Human) 25884
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