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Invitrogen
Carbonic Anhydrase III Polyclonal Antibody
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Product Details
PA5-82774
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CA3. Recombinant protein control fragment (Product #RP-92484).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DHWHELFPNA KGENQSPVEL HTKDIRHDPS LQPWSVSYDG GSAKTILNNG KTCRVVFDDT YDRSMLRGGP LPGPYR
Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.
Target Information
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10. 3 kb and contains seven exons and six introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA III; CA-III; CAH3; CAIII (Muscle); Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; carbonic anhydrase III, muscle specific; carbonic anhydrase IIII; EC 4.2.1.1; epididymis secretory sperm binding protein Li 167mP; HEL-S-167mP; unnamed protein product
Gene Aliases: CA3; CAIII; Car3
UniProt ID: (Human) P07451
Entrez Gene ID: (Human) 761
skeletal muscle contraction
response to oxidative stress
positive regulation of cell proliferation
response to bacterium
cellular response to insulin stimulus
response to lipid
negative regulation of apoptotic process
cellular response to leptin stimulus
response to ethanol
cellular response to hypoxia
response to alcohol
liver regeneration
negative regulation of reactive oxygen species biosynthetic process
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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