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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PDE1A Antibodies

          Invitrogen

          PDE1A Polyclonal Antibody

          View all (14) PDE1A antibodies

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          Cite PDE1A Polyclonal Antibody

          • Antibody Testing Data (2)
          PDE1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PDE1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          PDE1A Antibody (PA5-82794) in IHC (P)

          Immunohistochemical analysis of PDE1A in human thyroid gland using PDE1A Polyclonal Antibody (Product # PA5-82794) shows colloid positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PDE1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PDE1A Antibody in Western Blot (WB)

          Product Details

          PA5-82794

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PDE1A. Recombinant protein control fragment (Product #RP-89902).

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2789950

          Product Specific Information

          Immunogen sequence: RNLVIEMVLS TDMSGHFQQI KNIRNSLQQP EGIDRAKTMS LILHAADISH PAKSWKLHYR WTMALMEEFF LQGDKEAE

          Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 97%.

          Target Information

          Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1)that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: 61 kDa Cam-PDE; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; Cam-PDE 1A; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; hCam-1; HS MGC26303; MGC26303; phosphodiesterase 1A, calmodulin-dependent; phosphodiesterase-1A

          View more View less

          Gene Aliases: CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A; PDE1A

          View more View less

          UniProt ID: (Human) P54750

          View more View less

          Entrez Gene ID: (Human) 5136

          View more View less

          Function(s)
          3',5'-cyclic-AMP phosphodiesterase activity calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity phosphodiesterase
          Process(es)
          signal transduction
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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