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Invitrogen
hnRNP M Polyclonal Antibody
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Product Details
PA5-82878
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HNRNPM. Recombinant protein control fragment (Product #RP-102309).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NKMGGMEGPF GGGMENMGRF GSGMNMGRIN EILSNALKRG EIIAKQGGGG GGGSVPGIER MGPGIDRLGG AGMERMGAGL GHGMDRVGSE IERMGLVMDR MGSVE
Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 96%.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CEA receptor; Heterogeneous nuclear ribonucleoprotein M; heterogenous nuclear ribonucleoprotein M4; hnRNA-binding protein M4; hnRNP M; M4 protein; N-acetylglucosamine receptor 1
Gene Aliases: 2610023M21Rik; AA409009; CEAR; hnRNP M; HNRNPM; HNRNPM4; HNRPM; HNRPM4; HTGR1; mKIAA4193; NAGR1
UniProt ID: (Human) P52272, (Rat) Q62826, (Mouse) Q9D0E1
Entrez Gene ID: (Human) 4670, (Rat) 116655, (Mouse) 76936
alternative mRNA splicing, via spliceosome
mRNA splicing, via spliceosome
fibroblast growth factor receptor signaling pathway
gene expression
cellular response to lipopolysaccharide
positive regulation of protein localization to nucleus
positive regulation of protein import
cellular response to carcinoembryonic antigen
mRNA processing
RNA splicing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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