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          • Primary Antibodies ›
          • HJURP Antibodies

          Invitrogen

          HJURP Polyclonal Antibody

          View all (11) HJURP antibodies

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          Cite HJURP Polyclonal Antibody

          • Antibody Testing Data (1)
          HJURP Antibody in Immunocytochemistry (ICC/IF)
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          HJURP Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          HJURP Antibody (PA5-82963) in ICC/IF

          Immunofluorecent analysis of HJURP in human cell line RH-30 using HJURP Polyclonal Antibody (Product # PA5-82963). Staining shows localization to nucleus and nucleoli. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HJURP Antibody in Immunocytochemistry (ICC/IF)
          HJURP Polyclonal Antibody

          Product Details

          PA5-82963

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human HJURP. Recombinant protein control fragment (Product #RP-104578).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790119

          Product Specific Information

          Immunogen sequence: RKTGLKLEKA FLEVNRPQIH KLDPSWKERK VTPSKYSSLI YFDSSATYNL DEENRFRTLK WLISPVKIVS RPTIRQGHGE NRQREIEIRF DQLHREYCLS PRNQPRRMCL PDSWAMNMYR GGPASPGGLQ GLETRRLSLP SSKAKA

          Highest antigen sequence indentity to the following orthologs: Mouse - 45%, Rat - 45%.

          Target Information

          Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 14-3-3-associated AKT substrate; fetal liver expressing gene 1; Fetal liver-expressing gene 1 protein; Holliday junction recognition protein; Up-regulated in lung cancer 9

          View more View less

          Gene Aliases: FAKTS; FLEG1; hFLEG1; HJURP; URLC9

          View more View less

          UniProt ID: (Human) Q8NCD3

          View more View less

          Entrez Gene ID: (Human) 55355

          View more View less

          Function(s)
          DNA binding protein binding histone binding identical protein binding
          Process(es)
          cell cycle chromosome segregation CENP-A containing nucleosome assembly regulation of protein complex assembly regulation of DNA binding
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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