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Invitrogen
AZIN1 Polyclonal Antibody
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Product Details
PA5-82991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AZIN1. Recombinant protein control fragment (Product #RP-93830).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AKVGVNILTC DNEIELKKIA RNHPNAKVLL HIATEDNIGG EEGNMKFGTT LKNCRHLLEC AKELDVQIIG VKFHVSSACK ESQVYV
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 94%.
Target Information
Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antizyme inhibitor 1; AZI; O OAZIN; OAZIN; Ornithine decarboxylase antizyme inhibitor; similar to Homo sapiens antizyme inhibitor encoded by GenBank Accession Number D88674; unnamed protein product
Gene Aliases: AZI; AZI1; AZIA1; AZIN1; OAZI; OAZIN; ODC1L
UniProt ID: (Human) O14977
Entrez Gene ID: (Human) 51582
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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