Search
Invitrogen
SOX4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-83111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SOX4. Recombinant protein control fragment (Product #RP-94806).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VQQTNNAENT EALLAGESSD SGAGLELGIA SSPTPGSTAS TGGKADDPSW CKTPSGHIKR PMNAFMVWSQ IE
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 39%.
Target Information
SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of SOX genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 SOX genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ecotropic viral integration site 16; SRY (sex determining region Y)-box 4; SRY-box 4; SRY-related HMG-box gene 4; Transcription factor SOX-4
Gene Aliases: CSS10; EVI16; SOX4
UniProt ID: (Human) Q06945
Entrez Gene ID: (Human) 6659
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
miRNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
pro-B cell differentiation
mitral valve morphogenesis
cardiac right ventricle morphogenesis
atrial septum primum morphogenesis
noradrenergic neuron differentiation
regulation of transcription, DNA-templated
nervous system development
brain development
heart development
positive regulation of cell proliferation
gene expression
glial cell proliferation
spinal cord development
glial cell development
neuron differentiation
T cell differentiation
endocrine pancreas development
positive regulation of insulin secretion
somatic stem cell population maintenance
ascending aorta morphogenesis
glucose homeostasis
positive regulation of apoptotic process
regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of gamma-delta T cell differentiation
negative regulation of myoblast differentiation
positive regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
sympathetic nervous system development
camera-type eye morphogenesis
protein stabilization
ventricular septum morphogenesis
mesenchyme development
neuroepithelial cell differentiation
kidney morphogenesis
hematopoietic stem cell homeostasis
cellular response to glucose stimulus
positive regulation of canonical Wnt signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support