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          • Primary Antibodies ›
          • WDR74 Antibodies

          Invitrogen

          WDR74 Polyclonal Antibody

          View all (17) WDR74 antibodies

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          Cite WDR74 Polyclonal Antibody

          • Antibody Testing Data (3)
          WDR74 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          WDR74 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          WDR74 Antibody (PA5-83390) in IHC (P)

          Immunohistochemical analysis of WDR74 in human skeletal muscle using WDR74 Polyclonal Antibody (Product # PA5-83390) shows moderate cytoplasmic positivity in myocytes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          WDR74 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          WDR74 Antibody in Western Blot (WB)
          WDR74 Antibody in Western Blot (WB)
          WDR74 Polyclonal Antibody

          Product Details

          PA5-83390

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human WDR74. Recombinant protein control fragment (Product #RP-97331).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790546

          Product Specific Information

          Immunogen sequence: GGEGMFRGLA QADGTLITCV DSGILRVWHD KDKDTSSDPL LELRVGPGVC RMRQDPAHPH VVATGGKENA LKIWDL

          Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 84%.

          Target Information

          The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: NOP seven-associated protein 1; WD repeat-containing protein 74

          View more View less

          Gene Aliases: NSA1; WDR74

          View more View less

          UniProt ID: (Human) Q6RFH5

          View more View less

          Entrez Gene ID: (Human) 54663

          View more View less

          Function(s)
          molecular_function protein binding RNA processing factor
          Process(es)
          blastocyst formation biological_process RNA metabolic process ribosomal large subunit biogenesis
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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