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          • Primary Antibodies ›
          • DDX23 Antibodies

          Invitrogen

          DDX23 Polyclonal Antibody

          View all (8) DDX23 antibodies

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          Cite DDX23 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          DDX23 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          DDX23 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          DDX23 Antibody (PA5-83436) in IHC (P)

          Immunohistochemical analysis of DDX23 in human prostate using DDX23 Polyclonal Antibody (Product # PA5-83436) shows strong nuclear positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          DDX23 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          DDX23 Antibody in Western Blot (WB)
          DDX23 Polyclonal Antibody

          Product Details

          PA5-83436

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human DDX23. Recombinant protein control fragment (Product #RP-97849).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.7 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790591

          Product Specific Information

          Immunogen sequence: RNKKDRDRDK DGHRRDKDRK RSSLSPGRGK DFKSRKDRDS KKDEEDEHGD KKPKAQPLSL EELLAKKKAE EEAEAKPKFL SKAEREAEAL KRRQQ

          Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 93%.

          Target Information

          PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 100 kDa U5 snRNP-specific protein; DEAD (Asp-Glu-Ala-Asp) box polypeptide 23; DEAD box protein 23; DEAD-box, RS domain; Probable ATP-dependent RNA helicase DDX23; PRP28 homolog; PRP28 homolog, yeast; PRP28p homolog; U5 snRNP 100 kD protein; U5 snRNP-specific 100-kD protein; U5-100kD; unnamed protein product

          View more View less

          Gene Aliases: DDX23; prp28; PRPF28; SNRNP100; U5-100K; U5-100KD

          View more View less

          UniProt ID: (Human) Q9BUQ8

          View more View less

          Entrez Gene ID: (Human) 9416

          View more View less

          Function(s)
          nucleotide binding nucleic acid binding RNA binding RNA helicase activity mRNA binding helicase activity protein binding ATP binding hydrolase activity ATPase activity
          Process(es)
          cis assembly of pre-catalytic spliceosome RNA splicing, via transesterification reactions mRNA splicing, via spliceosome mRNA processing RNA splicing R-loop processing
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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