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Invitrogen
RAB3IP Polyclonal Antibody
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Product Details
PA5-83477
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RAB3IP. Recombinant protein control fragment (Product #RP-97740).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AEISSISFHV TDPAPCSTSG VTAGLTKLTT RKDNYNAERE FLQGATITEA CDGSDDIFGL STDSLSRLRS PSVLEVREKG YERLKEELAK AQ
Highest antigen sequence indentity to the following orthologs: Rat - 79%, Mouse - 80%.
Target Information
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAS64; Rab-3A-interacting protein; Rab3A-interacting protein; Rabin-3; Rabin8; SSX2 interacting protein; SSX2-interacting protein; unnamed protein product
Gene Aliases: RAB3IP; RABIN3; RABIN8
UniProt ID: (Human) Q96QF0
Entrez Gene ID: (Human) 117177
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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