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Invitrogen
SCN3B Polyclonal Antibody
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Product Details
PA5-83572
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SCN3B. Recombinant protein control fragment (Product #RP-108354).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RLQWNGSKDL QDVSITVLNV TLNDSGLYTC NVSREFEFEA HRPFVKTTRL IPLRVTEEAG EDFT
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sodium channel regulatory subunit beta-3; sodium channel subunit beta-3; sodium channel, voltage-gated, type III, beta subunit; unnamed protein product; voltage-gated sodium channel beta-3 subunit
Gene Aliases: ATFB16; BRGDA7; HSA243396; KIAA1158; SCN3B; SCNB3
UniProt ID: (Human) Q9NY72
Entrez Gene ID: (Human) 55800
ion transport
sodium ion transport
nervous system development
positive regulation of heart rate
positive regulation of sodium ion transport
ion transmembrane transport
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
cardiac conduction
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell action potential
regulation of heart rate by cardiac conduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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