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Invitrogen
SMYD3 Polyclonal Antibody
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Product Details
PA5-83795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMYD3. Recombinant protein control fragment (Product #RP-106098).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AMCQAIISSN SERLPDINIY QLKVLDCAMD ACINLGLLEE ALFYGTRTME PYRIFFPGSH PVRGVQVMKV GKLQLHQGMF PQAMKNLRLA FDIM
Highest antigen sequence indentity to the following orthologs: Rat - 27%, Mouse - 94%.
Target Information
SMYD3 (histone-lysine N-methyltransferase) methylates Lys-4 of histone H3 and Lys-5 of histone H4. It induces di- and tri-methylation. SMYD3 plays an important role in transcriptional activation as a member of an RNA polymerase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Histone-lysine N-methyltransferase SMYD3; SET and MYND domain-containing protein 3; SET domain; unnamed protein product; Zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1
Gene Aliases: bA74P14.1; KMT3E; SMYD3; ZMYND1; ZNFN3A1
UniProt ID: (Human) Q9H7B4
Entrez Gene ID: (Human) 64754
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core binding
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
protein binding
methyltransferase activity
zinc ion binding
transferase activity
histone methyltransferase activity
metal ion binding
histone H4 methyltransferase activity
histone H3K36 dimethyltransferase activity
histone H3K4 trimethyltransferase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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