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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • RSPO1 Antibodies

          Invitrogen

          RSPO1 Polyclonal Antibody

          View all (8) RSPO1 antibodies

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          Cite RSPO1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          RSPO1 Antibody (PA5-83809) in IHC (P)

          Immunohistochemical analysis of RSPO1 in human adrenal gland using RSPO1 Polyclonal Antibody (Product # PA5-83809) shows strong cytoplasmic positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RSPO1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RSPO1 Polyclonal Antibody

          Product Details

          PA5-83809

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human RSPO1. Recombinant protein control fragment (Product #RP-94446).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790961

          Product Specific Information

          Immunogen sequence: CKEGLYLHKG RCYPACPEGS SAANGTMECS SPAQCEMSEW SPWGPCSKKQ QLCGFRRGSE ERTRRVLHA

          Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 90%.

          Target Information

          This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: FLJ40906; hRspo1; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1

          View more View less

          Gene Aliases: CRISTIN3; RSPO; RSPO1

          View more View less

          UniProt ID: (Human) Q2MKA7

          View more View less

          Entrez Gene ID: (Human) 284654

          View more View less

          Function(s)
          G-protein coupled receptor binding receptor binding protein binding heparin binding
          Process(es)
          positive regulation of protein phosphorylation regulation of receptor internalization Wnt signaling pathway positive regulation of Wnt signaling pathway positive regulation of canonical Wnt signaling pathway
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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