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Invitrogen
RPA70 Polyclonal Antibody
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Product Details
PA5-83821
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RPA1. Recombinant protein control fragment (Product #RP-104820).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PVLAIKGARV SDFGGRSLSV LSSSTIIANP DIPEAYKLRG WFDAEGQALD GVSISDLKSG GVGGSNTNWK TLYEVKSENL GQGDKPDYFS SVATVVYLRK ENCMYQACPT QDCNKKVIDQ QNGLYRCEK
Highest antigen sequence indentity to the following orthologs: Rat - 91%, Mouse - 89%.
Target Information
This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MSTP075; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit; replication protein A1, 70kDa; RF-A protein 1; RP-A p70; Single-stranded DNA-binding protein
Gene Aliases: HSSB; MST075; REPA1; RF-A; RP-A; RPA1; RPA70
UniProt ID: (Human) A8K0Y9
Entrez Gene ID: (Human) 6117
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA replication
DNA-dependent DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
DNA recombination
protein sumoylation
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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