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Invitrogen
SAMHD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-83852
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SAMHD1. Recombinant protein control fragment (Product #RP-99320).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DDSPRTPSNT PSAEADWSPG LELHPDYKTW GPEQVCSFLR RGGFEEPVLL KNIRENEITG ALLPCLDESR FENLGVSSLG ERKKLLSYIQ RLVQIHVDTM KVI
Highest antigen sequence indentity to the following orthologs: Mouse - 52%, Rat - 52%.
Target Information
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dendritic cell-derived IFNG-induced protein; dNTPase; monocyte protein 5; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; unnamed protein product
Gene Aliases: CHBL2; DCIP; HDDC1; hSAMHD1; MOP-5; SBBI88
UniProt ID: (Human) Q9Y3Z3
Entrez Gene ID: (Human) 25939
double-strand break repair via homologous recombination
dGTP catabolic process
immune response
cellular response to DNA damage stimulus
deoxyribonucleotide catabolic process
somatic hypermutation of immunoglobulin genes
regulation of innate immune response
dATP catabolic process
protein homotetramerization
defense response to virus
negative regulation of type I interferon-mediated signaling pathway
DNA strand resection involved in replication fork processing
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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