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Invitrogen
Drebrin Polyclonal Antibody
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Product Details
PA5-84067
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DBN1. Recombinant protein control fragment (Product #RP-103099).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PSPILDSEET RAAAPQAWAG PMEEPPQAQA PPRGPGSPAE DLMFMESAEQ AVLAAPVEPA TADATEIHDA ADTIETDTAT ADTTVANNVP PAATSLIDLW P
Highest antigen sequence indentity to the following orthologs: Mouse - 61%, Rat - 61%.
Target Information
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin E; drebrin E2; drebrin-1
Gene Aliases: D0S117E; DBN1
UniProt ID: (Human) Q16643
Entrez Gene ID: (Human) 1627
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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