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Invitrogen
PLA2G5 Polyclonal Antibody
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Product Details
PA5-84150
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLA2G5. Recombinant protein control fragment (Product #RP-99794).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GLLDLKSMIE KVTGKNALTN YGFYGCYC
Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 86%.
Target Information
This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca2+-dependent phospholipase A2; DKFZp686C2294; MGC46205; Phosphatidylcholine 2-acylhydrolase 5; Phospholipase A2 group V; phospholipase A2, group V; PLA2-10
Gene Aliases: FRFB; GV-PLA2; hVPLA(2); PLA2-10; PLA2G5
UniProt ID: (Human) P39877
Entrez Gene ID: (Human) 5322
phospholipid metabolic process
phosphatidic acid biosynthetic process
platelet activating factor biosynthetic process
positive regulation of phospholipase activity
lipid catabolic process
leukotriene biosynthetic process
response to cytokine
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
arachidonic acid secretion
response to cAMP
positive regulation of ERK1 and ERK2 cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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