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Invitrogen
TPM1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-84164
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TPM1. Recombinant protein control fragment (Product #RP-104195).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LNRRIQLVEE ELDRAQERLA TALQKLEE
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiomyopathy, hypertrophic 3; epididymis secretory protein Li 265; myofibrillar protein; component of thin filaments; alternatively spliced; sarcomeric tropomyosin kappa; skeletal muscle tropomyosin; TPM1-alpha; tropomyosin; tropomyosin 1 (alpha) isoform TPM1_1; tropomyosin 1 (alpha) isoform TPM1_2; unnamed protein product
Gene Aliases: C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA
UniProt ID: (Human) P09493
Entrez Gene ID: (Human) 7168
positive regulation of heart rate by epinephrine
regulation of muscle contraction
cytoskeleton organization
actin filament organization
regulation of heart contraction
regulation of cell shape
muscle filament sliding
negative regulation of cell migration
ruffle organization
cellular response to reactive oxygen species
wound healing
sarcomere organization
positive regulation of cell adhesion
positive regulation of stress fiber assembly
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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