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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GTTTTTTSVK KEELVPSEED FQGITPGAQG PSSRGREPEA RPKRELRERE GPSLGPP
Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 75%.
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 95 kDa retinoblastoma-associated protein; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; MGC13051; RBP95; RING finger protein 40; RING-type E3 ubiquitin transferase BRE1B
Gene Aliases: BRE1B; KIAA0661; RNF40
Entrez Gene ID: (Human) 9810
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