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Invitrogen
TAF1A Polyclonal Antibody
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Product Details
PA5-84194
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAF1A. Recombinant protein control fragment (Product #RP-94292).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HQWQQAAEYM YSYFQTLEDS DSYKRQAAPE IIWKLGSEIL FYHPKSNMES FNTFANRMKN IGVMNYLKIS LQHALYLLHH GMLKDAKRNL SE
Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 87%.
Target Information
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, also known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RNA polymerase I-specific TBP-associated factor 48 kDa; SL1, 48kD subunit; TAFI48; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein associated factor 1A; TATA box-binding protein-associated factor 1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; TATA-box binding protein associated factor, RNA polymerase I, A; TBP-associated factor 1A; Transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit A
Gene Aliases: MGC:17061; RAFI48; SL1; TAF1A; TAFI48
UniProt ID: (Human) Q15573
Entrez Gene ID: (Human) 9015
regulation of transcription, DNA-templated
transcription from RNA polymerase I promoter
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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